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Skip anchors better#4899

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faithokamoto wants to merge 5 commits intomasterfrom
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Open

Skip anchors better#4899
faithokamoto wants to merge 5 commits intomasterfrom
skip-better

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To be copied to the draft changelog by merger:

Description

Fixes the calculation called out in #4701. I added another parameter in the process because I was doing a parameter search. Didn't take out out again mostly because I didn't want to bother. It's not hurting anyone.

Fiddling with the parameters revealed no clear wins on HiFi reads, and on R10 reads the best I got was about an extra bp/read which was aligned as a match (plus 0.5bp/read less softclips), with no real compromises elsewhere. (Google Sheets) Which is technically a win but is so small that I'm not bothering updating the parameters. So the PR is just the bugfix.

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Graph distance logic for skipping repetitive anchors in Giraffe doesn't account for the anchor length itself

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