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blastp

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This project applies bioinformatics techniques to analyze biological sequences, including protein structure prediction, sequence alignment, and comparative genomics using tools like BLASTP, AlphaFold3, and BioPython. It combines algorithmic methods with practical applications in computational genomics.

  • Updated Jun 22, 2025
  • Python

Computational analysis and classification of Variants of Unknown Significance (VUS) in the BCS1L gene associated with Björnstad Syndrome. Implements a conservation score-based algorithm using BLASTp homologous sequences, MUSCLE alignment, and phylogenetic analysis to classify variants as pathogenic or benign.

  • Updated Mar 10, 2026

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