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proteosim

Proteosim Course Package

with the functions in this package we can simulate a MS. It includes reading Fasta files with seqences, digesting them and calculating the m/z values and retention times.

installation instructions: pip install -r requirements.txt pip install

input: FASTA file processing steps: digestion, chromatography, MS simulation outputs: mz tables, fragment spectra

overview functions:

protein digestion -digest_protein_sequence, -digest_protein_collection, -compute_sequence_coverage,

liquid_chromatography -predict_lc_retention_times, -plot_retention_time, -select_retention_time_window

mass_spectra_simulation -amino_acid_mass_dalton, -calculate_mol_mass, -calculate_mol_mass_collection, -calculate_mz_collection, -fragment_peptide, -plot_spectrum

experimet notebook: ms_experiment_final.ipynb

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