Hi,
I was wondering if your tool would be appropriate to downsample ONT samples at different coverages (0.1x, 0.5x, 1x, 3x, 5x among others) and then call CNVs to compare. I understand this would fall under Example Use 8 but I was wondering:
- Would the subsample occur evenly across all the genome?
- Would the subsample "erase" CNV duplications by effectively getting an average coverage across the genome? Or is it possible to downsample but keeping these changes present?
Many thanks in advance.
Best,
Pablo
Hi,
I was wondering if your tool would be appropriate to downsample ONT samples at different coverages (0.1x, 0.5x, 1x, 3x, 5x among others) and then call CNVs to compare. I understand this would fall under Example Use 8 but I was wondering:
Many thanks in advance.
Best,
Pablo