I have some humongous node trees that I tried arranging with this addon, and I noticed that it doesn't pay any attention to the frames.
This would be way more useful if it did, as currently it only makes sense to use it on simple node trees.
After arranging (with tweaked and optimized settings):

EDIT:
Perhaps this can work by recursively arranging the nodes; first the ones in the innermost frame, then the frame that contains that, (treating contained frames as whole nodes).
I have some humongous node trees that I tried arranging with this addon, and I noticed that it doesn't pay any attention to the frames.
This would be way more useful if it did, as currently it only makes sense to use it on simple node trees.
After arranging (with tweaked and optimized settings):

EDIT:
Perhaps this can work by recursively arranging the nodes; first the ones in the innermost frame, then the frame that contains that, (treating contained frames as whole nodes).