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This repository was archived by the owner on Mar 12, 2026. It is now read-only.
This repository was archived by the owner on Mar 12, 2026. It is now read-only.

Fail loading index ('dna_compression.bin' file is empty) #16

@jaudoux

Description

@jaudoux

Dear HPG developpers,

I am experiencing some trouble to execute HPG-aligner on RNA mode. The following error quickly shows up during the execution :

Fri Feb 5 11:27:43 2016 FATAL lib/hpg-libs/bioinfo-libs/aligners/bwt/genome.c [413] in load_binary_dna(): Error, '/data/indexes/HPG//GRCh38//dna_compression.bin' file is empty!

This is the command line I have been using:

hpg-aligner rna -i /data/indexes/HPG//GRCh38/ -t 20 -o hpg -f simulation/reads_1.fastq.gz -j simulation/reads_2.fastq.gz -z

The index has been constructed using the SA (default) mode, this is the content of my index directory:

-rw-rw-r-- 1 jaudoux users           0 févr.  2 10:20 dna_compression.bin
-rw-rw-r-- 1 jaudoux users  8088051536 févr.  2 10:20 GRCh38.fa.A
-rw-rw-r-- 1 jaudoux users  2937639113 févr.  2 10:05 GRCh38.fa.CHROM
-rw-rw-r-- 1 jaudoux users  1073741824 févr.  2 10:20 GRCh38.fa.IA
-rw-rw-r-- 1 jaudoux users  2022012884 févr.  2 10:20 GRCh38.fa.JA
-rw-rw-r-- 1 jaudoux users  3088269734 févr.  2 09:44 GRCh38.fa.S
-rw-rw-r-- 1 jaudoux users 11750556452 févr.  2 10:04 GRCh38.fa.SA
-rw-rw-r-- 1 jaudoux users         365 févr.  2 10:20 index
-rw-rw-r-- 1 jaudoux users         206 févr.  2 09:39 Makefile
-rw-rw-r-- 1 jaudoux users         289 févr.  2 10:20 params.info
-rw-rw-r-- 1 jaudoux users         354 févr.  2 10:20 params.txt

Thank you in advance for your help,
Jérôme.

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