Hello,
Thank you for the interesting AgregateBioVar paper.
This is more of a question than an issue. I had looked at the vignette and I was wondering, how was the new suggested modeling framework (your proposed extension of the negative binomial) incorporated into the DS analysis framework? In the vignette, I can see that counts were aggregated by the aggregatebioVar() and then DE was done using DESeq().
Hello,
Thank you for the interesting AgregateBioVar paper.
This is more of a question than an issue. I had looked at the vignette and I was wondering, how was the new suggested modeling framework (your proposed extension of the negative binomial) incorporated into the DS analysis framework? In the vignette, I can see that counts were aggregated by the
aggregatebioVar()and then DE was done usingDESeq().