diff --git a/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyEntryBasic.java b/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyEntryBasic.java
index 74db49a6c4..c06c828e2c 100644
--- a/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyEntryBasic.java
+++ b/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyEntryBasic.java
@@ -41,7 +41,7 @@ final class NaturalKeyEntryBasic implements NaturalKeyEntry {
    * Create when query uses an IN PAIRS clause.
    */
   NaturalKeyEntryBasic(BeanNaturalKey naturalKey, List<NaturalKeyEq> eqList,
-                        String inMapProperty0, String inMapProperty1, Pairs.Entry pair) {
+                       String inMapProperty0, String inMapProperty1, Pairs.Entry pair) {
     load(eqList);
     map.put(inMapProperty0, pair.getA());
     map.put(inMapProperty1, pair.getB());
@@ -49,6 +49,14 @@ final class NaturalKeyEntryBasic implements NaturalKeyEntry {
     this.key = calculateKey(naturalKey);
   }
 
+  NaturalKeyEntryBasic(BeanNaturalKey naturalKey, List<NaturalKeyEq> eqList,
+                       Map<String, Object> properties, Object[] naturalKeyValue) {
+    load(eqList);
+    map.putAll(properties);
+    this.inValue = naturalKeyValue;
+    this.key = calculateKey(naturalKey);
+  }
+
   private void load(List<NaturalKeyEq> eqList) {
     if (eqList != null) {
       for (NaturalKeyEq eq : eqList) {
diff --git a/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyQueryData.java b/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyQueryData.java
index c7989557ac..46c1357abf 100644
--- a/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyQueryData.java
+++ b/ebean-core/src/main/java/io/ebeaninternal/api/NaturalKeyQueryData.java
@@ -3,10 +3,7 @@
 import io.ebean.Pairs;
 import io.ebeaninternal.server.deploy.BeanNaturalKey;
 
-import java.util.ArrayList;
-import java.util.HashSet;
-import java.util.List;
-import java.util.Set;
+import java.util.*;
 
 /**
  * Collects the data for processing the natural key cache processing.
@@ -19,8 +16,9 @@ public final class NaturalKeyQueryData<T> {
    */
   private boolean hasIn;
   // IN Pairs clause - only one allowed
-  private String inProperty0, inProperty1;
   private List<Pairs.Entry> inPairs;
+  private String[] properties;
+  private List<Object[]> inTuples;
   // IN clause - only one allowed
   private List<Object> inValues;
   private String inProperty;
@@ -47,14 +45,39 @@ public List<Pairs.Entry> matchInPairs(String property0, String property1, List<P
     }
     if (matchProperty(property0) && matchProperty(property1)) {
       this.hasIn = true;
-      this.inProperty0 = property0;
-      this.inProperty1 = property1;
+      this.properties = new String[]{property0, property1};
       this.inPairs = new ArrayList<>(inPairs); // will be modified
       return this.inPairs;
     }
     return null;
   }
 
+  /**
+   * Match for In Tuples expression. We only allow one IN clause.
+   */
+  public List<Object[]> matchInTuples(String[] properties, List<Object[]> inTuples) {
+    if (hasIn) {
+      // only 1 IN allowed (to project naturalIds)
+      return null;
+    }
+
+    boolean matchAll = true;
+
+    for (String property : properties) {
+      if (!matchProperty(property)) {
+        matchAll = false;
+        break;
+      }
+    }
+    if (matchAll) {
+      this.hasIn = true;
+      this.properties = Arrays.copyOf(properties, properties.length);
+      this.inTuples = new ArrayList<>(inTuples);
+      return this.inTuples;
+    }
+    return null;
+  }
+
   /**
    * Match for IN expression. We only allow one IN clause.
    */
@@ -100,6 +123,8 @@ public NaturalKeySet buildKeys() {
       addInValues();
     } else if (inPairs != null) {
       addInPairs();
+    } else if (inTuples != null) {
+      addInTuples();
     } else {
       addEqualsKey();
     }
@@ -110,7 +135,17 @@ private void addInPairs() {
     // a findList() with an IN Map clause so we project
     // for every IN value a natural key combination
     for (Pairs.Entry entry : inPairs) {
-      set.add(new NaturalKeyEntryBasic(naturalKey, eqList, inProperty0, inProperty1, entry));
+      set.add(new NaturalKeyEntryBasic(naturalKey, eqList, properties[0], properties[1], entry));
+    }
+  }
+
+  private void addInTuples() {
+    for (Object[] inTuple : inTuples) {
+      Map<String, Object> map = new HashMap<>();
+      for (int i = 0; i < inTuple.length; i++) {
+        map.put(properties[i], inTuple[i]);
+      }
+      set.add(new NaturalKeyEntryBasic(naturalKey, eqList, map, inTuple));
     }
   }
 
@@ -152,11 +187,8 @@ private boolean matchProperties() {
     if (inProperty != null) {
       exprProps.add(inProperty);
     }
-    if (inProperty0 != null) {
-      exprProps.add(inProperty0);
-    }
-    if (inProperty1 != null) {
-      exprProps.add(inProperty1);
+    if (properties != null) {
+      exprProps.addAll(Arrays.asList(properties));
     }
     if (eqList != null) {
       for (NaturalKeyEq eq : eqList) {
@@ -173,6 +205,7 @@ private boolean expressionCount() {
     int defined = (inValues == null) ? 0 : 1;
     defined += (inPairs == null) ? 0 : 2;
     defined += (eqList == null) ? 0 : eqList.size();
+    defined += (inTuples == null) ? 0 : properties.length;
     return defined == naturalKey.length();
   }
 
@@ -206,6 +239,9 @@ private void removeKey(Object inValue) {
     } else if (inPairs != null) {
       //noinspection SuspiciousMethodCalls
       inPairs.remove(inValue);
+    } else if (inTuples != null) {
+      //noinspection SuspiciousMethodCalls
+      inTuples.remove(inValue);
     }
   }
 }
diff --git a/ebean-core/src/main/java/io/ebeaninternal/server/expression/InTuplesExpression.java b/ebean-core/src/main/java/io/ebeaninternal/server/expression/InTuplesExpression.java
index f1765f3f9c..e42a5aae8f 100644
--- a/ebean-core/src/main/java/io/ebeaninternal/server/expression/InTuplesExpression.java
+++ b/ebean-core/src/main/java/io/ebeaninternal/server/expression/InTuplesExpression.java
@@ -12,7 +12,7 @@ final class InTuplesExpression extends AbstractExpression {
 
   private final boolean not;
   private final String[] properties;
-  private final List<Object[]> entries;
+  private List<Object[]> entries;
 
   InTuplesExpression(InTuples pairs, boolean not) {
     super("");
@@ -25,7 +25,15 @@ final class InTuplesExpression extends AbstractExpression {
 
   @Override
   public boolean naturalKey(NaturalKeyQueryData<?> data) {
-    return false;
+    if (not) {
+      return false;
+    }
+    List<Object[]> copy = data.matchInTuples(properties, entries);
+    if (copy == null) {
+      return false;
+    }
+    entries = copy;
+    return true;
   }
 
   @Override
diff --git a/ebean-redis/src/test/java/org/integration/IntegrationTest.java b/ebean-redis/src/test/java/org/integration/IntegrationTest.java
index 8add988b32..78f1b0a956 100644
--- a/ebean-redis/src/test/java/org/integration/IntegrationTest.java
+++ b/ebean-redis/src/test/java/org/integration/IntegrationTest.java
@@ -1,6 +1,8 @@
 package org.integration;
 
 import io.ebean.DB;
+import io.ebean.InTuples;
+import io.ebean.Pairs;
 import io.ebean.cache.ServerCache;
 import io.ebean.cache.ServerCacheStatistics;
 import org.domain.*;
@@ -177,6 +179,76 @@ private static OtherOne findOther(String a, String b) {
       .findOne();
   }
 
+  @Test
+  void naturalKey_inPairs() throws InterruptedException {
+    DB.save(new OtherOne("ip_A", "ip_1", "ip_A1"));
+    DB.save(new OtherOne("ip_A", "ip_2", "ip_A2"));
+    DB.save(new OtherOne("ip_B", "ip_1", "ip_B1"));
+
+    ServerCache nkeyCache = DB.cacheManager().naturalKeyCache(OtherOne.class);
+    nkeyCache.clear();
+
+    Pairs pairs = new Pairs("one", "two")
+      .add("ip_A", "ip_1")
+      .add("ip_A", "ip_2")
+      .add("ip_B", "ip_1");
+
+    // first fetch — miss, populates natural key + bean cache
+    List<OtherOne> list0 = DB.find(OtherOne.class)
+      .where()
+      .inPairs(pairs)
+      .setUseCache(true)
+      .findList();
+    assertThat(list0).hasSize(3);
+    nkeyCache.statistics(true); // reset stats
+
+    Thread.sleep(5);
+
+    // second fetch — all three should hit the natural key cache
+    List<OtherOne> list1 = DB.find(OtherOne.class)
+      .where()
+      .inPairs(pairs)
+      .setUseCache(true)
+      .findList();
+    assertThat(list1).hasSize(3);
+    assertThat(nkeyCache.statistics(true).getHitCount()).isEqualTo(3);
+  }
+
+  @Test
+  void naturalKey_inTuples() throws InterruptedException {
+    DB.save(new OtherOne("it_A", "it_1", "it_A1"));
+    DB.save(new OtherOne("it_A", "it_2", "it_A2"));
+    DB.save(new OtherOne("it_B", "it_1", "it_B1"));
+
+    ServerCache nkeyCache = DB.cacheManager().naturalKeyCache(OtherOne.class);
+    nkeyCache.clear();
+
+    InTuples tuples = InTuples.of("one", "two")
+      .add("it_A", "it_1")
+      .add("it_A", "it_2")
+      .add("it_B", "it_1");
+
+    // first fetch — miss, populates natural key + bean cache
+    List<OtherOne> list0 = DB.find(OtherOne.class)
+      .where()
+      .inTuples(tuples)
+      .setUseCache(true)
+      .findList();
+    assertThat(list0).hasSize(3);
+    nkeyCache.statistics(true); // reset stats
+
+    Thread.sleep(5);
+
+    // second fetch — all three should hit the natural key cache
+    List<OtherOne> list1 = DB.find(OtherOne.class)
+      .where()
+      .inTuples(tuples)
+      .setUseCache(true)
+      .findList();
+    assertThat(list1).hasSize(3);
+    assertThat(nkeyCache.statistics(true).getHitCount()).isEqualTo(3);
+  }
+
   @Test
   void test() throws InterruptedException {