The pipeline currently feeds/starts PRISM with a complete reference genome. PRISM however does the analysis only per chromosome.
When it is started with a full reference genome, PRISM will produce segfaults (due memory limit in python with detect_sv.py)
Proposed solution:
Initiate the analysis with PRISM by first dividing the genome in individual chromsomes/contig-files.
Start analysis per contig
Merge results from all contig analyses
Report back to main pipeline.
The pipeline currently feeds/starts PRISM with a complete reference genome. PRISM however does the analysis only per chromosome.
When it is started with a full reference genome, PRISM will produce segfaults (due memory limit in python with detect_sv.py)
Proposed solution:
Initiate the analysis with PRISM by first dividing the genome in individual chromsomes/contig-files.
Start analysis per contig
Merge results from all contig analyses
Report back to main pipeline.